Name : KLHL25 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5750152816
| Long name | KLHL25 Primary Polyclonal Antibody |
| Also known as | KLHL25 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | KLHL25 |
| Specificity | This is a highly specific antibody against KLHL25 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 435-485/589 |
| Subcellular location | Intracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KLHL25 |
| Gene ID number | 64410 |
| Swiss Prot | Q9H0H3 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E, The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low, Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ENC-2, Ectoderm-neural cortex protein 2, KLHL25, Kelch-like protein 25, ENC2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | KLHL25 |
| Short name | KLHL25 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | KLHL25 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 25732 |
| Gene | KLHL25 |
| Long gene name | kelch like family member 25 |
| Synonyms gene name | kelch-like 25 (Drosophila) |
| Synonyms | FLJ12587 ENC2 ENC-2 |
| Synonyms name | ectodermal-neural cortex 2 |
| Locus | 15q25, 3 |
| Discovery year | 2005-11-17 |
| Entrez gene record | 64410 |
| RefSeq identity | NM_022480 |
| Classification | BTB domain containing Kelch like |
| Havana BLAST/BLAT | OTTHUMG00000148672 |