| Long name | KRAS Primary Polyclonal Antibody |
| Also known as | KRAS PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | KRAS |
| Specificity | This is a highly specific antibody against KRAS |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 1-50/189 |
| Subcellular location | Cell membrane, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human K-ras |
| Gene ID number | 3845 |
| Swiss Prot | P01116 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838), Ras proteins bind GDP/GTP and possess intrinsic GTPase activity |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | C-K-RAS, CFC2, GTPase KRas, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras 2, KI-RAS, KRAS, KRAS1, KRAS2, NS3, RASK2, c-Ki-ras, NS |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | KRAS |
| Short name | KRAS Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | C-K-RAS and CFC2 and K-RAS2A and K-RAS2B and K-RAS4A and K-RAS4B and KI-RAS and KRAS1 and KRAS2 and NS and NS3 and RASK2, GABAergic and biological process this GO :0032403 and protein complex binding and molecular function this GO :0035022 and positive regulation of Rac protein signal transduction and biological process this GO :0035176 and social behavior and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048169 and regulation of long-term neuronal synaptic plasticity and biological process this GO :0050900 and leukocyte migration and biological process this GO :0051000 and positive regulation of nitric-oxide synthase activity and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051146 and striated muscle cell differentiation and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0051385 and response to mineralocorticoid and biological process this GO :0060441 and epithelial tube branching involved in lung morphogenesis and biological process, KRAS and IDBG-23889 and ENSG00000133703 and 3845, KRAS and IDBG-638783 and ENSBTAG00000009778 and 541140, Kras and IDBG-197719 and ENSMUSG00000030265 and 16653, Plasma membranes, protein complex binding, this GO :0000165 and MAPK cascade and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0006913 and nucleocytoplasmic transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008542 and visual learning and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0015031 and protein transport and biological process this GO :0016020 and membrane and cellular component this GO :0019002 and GMP binding and molecular function this GO :0019003 and GDP binding and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030275 and LRR domain binding and molecular function this GO :0032228 and regulation of synaptic transmission, this GO :0003924: GTPase activity, this GO :0003924: GTPase activity and also this GO :0005515: protein binding and also this GO :0005525: GTP binding and also this GO :0019002: GMP binding and also this GO :0019003: GDP binding and also this GO :0030275: LRR domain binding and also this GO :0032403: protein complex binding, this GO :0005515: protein binding, this GO :0005525: GTP binding, this GO :0019002: GMP binding, this GO :0019003: GDP binding, this GO :0030275: LRR domain binding, this GO :0032403: protein complex binding, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog |
| Identity | 6407 |
| Gene | KRAS |
| Long gene name | GTPase , KRAS proto-oncogene |
| Synonyms gene | KRAS2 |
| Synonyms gene name | v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog Kirsten rat sarcoma viral oncogene homolog |
| Synonyms | KRAS1 |
| Locus | 12p12, 1 |
| Discovery year | 1988-06-02 |
| GenBank acession | BC010502 |
| Entrez gene record | 3845 |
| RefSeq identity | NM_033360 |
| Classification | RAS type GTPase family |
| Havana BLAST/BLAT | OTTHUMG00000171193 |
| Locus Specific Databases | LRG_344 |
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