Name : LRRTM3 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7865267115
| Long name | LRRTM3 Primary Polyclonal Antibody |
| Also known as | LRRTM3 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | LRRTM3 |
| Specificity | This is a highly specific antibody against LRRTM3 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LRRTM3 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | All LRR repeats contain a variable segment and a highly conserved segment, As a result of alternative splicing events, Expressed in neuronal tissues, LRRTM family members are known to exhibit synaptogenic activity, LRRTM3 (leucine rich repeat transmembrane neuronal 3) is a 581 amino acid single-pass type I membrane protein belonging to the LRRTM family, LRRTM3 is encoded by a gene that maps to a region of chromosome 10 that has been linked to late-onset Alzheimer disease and elevated plasma Beta-Amyloid, LRRTM3 is involved in the development and maintenance of the vertebrate nervous system, Localizing predominantly to the nervous system, The LRRTM protein family plays a role in the regulation of various cellular events during nervous system development, allowing it to accommodate several leucine residues within a tightly packed core, and contains ten LRR repeats, the latter of which accounts for 11 or 12 residues of the entire LRR motif, two LRRTM3 isoforms exist, The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | LRRT3_HUMAN, Leucine-rich repeat transmembrane neuronal protein 3, Lrrtm3, MGC131810, PRO1693, UNQ803, Leucine rich repeat transmembrane neuronal protein 3 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | LRRTM3 |
| Short name | LRRTM3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | LRRTM3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 19410 |
| Gene | LRRTM3 |
| Long gene name | leucine rich repeat transmembrane neuronal 3 |
| Locus | 10q21, 3 |
| Discovery year | 2004-02-04 |
| GenBank acession | BX640611 |
| Entrez gene record | 347731 |
| Pubmed identfication | 12676565 |
| RefSeq identity | NM_178011 |
| Havana BLAST/BLAT | OTTHUMG00000018332 |