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MAP1A/MAP1B LC3 A/B Antibody

MAP1A/MAP1B LC3 A/B Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameMAP1A/MAP1B LC3 A/B Antibody
Also known asMAP1A/MAP1B LC3 A/B Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMAP1A/MAP1B LC3 A/B
SpecificityThis is a highly specific antibody against MAP1A/MAP1B LC3 A/B
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range20-70/121
Subcellular location Cell membrane, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAP1A/MAP1B LC3 B
Gene ID number81631, 84557
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A disruption to the autophagic process is now associated with the progression of several cancers, LC3, LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), This process of internal cellular turn-over is called autophagy (self-eating), a ubiquitin-like modifier protein, and is facilitated by a pathway of around 16 interacting proteins in the human, called autophagosomes, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, neurodegenerative disorders and cardiac pathologies, respectively, termed LC3-I and LC3-II, where LC3 is widely employed as a marker for autophagy, which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Autophagy related protein LC3 A, Autophagy related protein LC3 B, Autophagy related ubiquitin like modier LC3 A, Autophagy related ubiquitin like modier LC3 B, LC3, MAP1 light chain 3 like protein 1, MAP1 light chain 3 like protein 2, MAP1A/1B light chain 3 A, MAP1A/1B light chain 3 B, MAP1A/1BLC3, MAP1A/MAP1B LC3 A, MAP1A/MAP1B LC3 B, MAP1ALC3, MAP1BLC3, MAP1LC3A, MAP1LC3B, Microtubule associated protein 1 light chain 3 alpha, Microtubule associated protein 1 light chain 3 beta, Microtubule associated proteins 1A/1B light chain 3, Microtubule associated proteins 1A/1B light chain 3A, Microtubule associated proteins 1A/1B light chain 3B, MAP LC3 beta, microtubule-associated proteins 1A/1B light chain 3 beta 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMAP1A/MAP1B LC3 A/B
Short nameMAP1A/MAP1B LC3 A/B Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMAP1A/MAP1B LC3 A/B (Antibody to)
Alternative techniqueantibodies
Identity 6835
Gene MAP1A
Long gene name microtubule associated protein 1A
Synonyms gene MAP1L
Locus 15q15, 3
Discovery year 1992-07-09
GenBank acession U38292
Entrez gene record 4130
Pubmed identfication 7806212 7629894
RefSeq identity NM_002373
Havana BLAST/BLAT OTTHUMG00000059756

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