Name : MEGF10 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1374116057
| Long name | MEGF10 Primary Polyclonal Antibody |
| Also known as | MEGF10 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MEGF10 |
| Specificity | This is a highly specific antibody against MEGF10 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MEGF10 |
| Gene ID number | 84466 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | It is expressed at the cell surface in clusters around cell corpses during engulfment, MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain, MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern, The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1), The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup, which is an ortholog to CED-7, 140 amino acid protein encoded by the human gene MEGF10, MEGF10 is a 1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | MEGF protein, Multiple EGF-like domains protein 10, Multiple epidermal growth factor-like domains 10, Multiple epidermal growth factor-like domains protein 10, megf10, multiple EGF-like-domains 10, MEG10_HUMAN |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MEGF10 |
| Short name | MEGF10 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | multiple epidermal growth factor-like-domains 10 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | MEGF10 and IDBG-39569 and ENSG00000145794 and 84466, MEGF10 and IDBG-644881 and ENSBTAG00000000329 and 539136, Megf10 and IDBG-148090 and ENSMUSG00000024593 and 70417, Plasma membranes, protein binding, this GO :0001891 and pha this GO cytic cup and cellular component this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0014719 and satellite cell activation and biological process this GO :0014816 and satellite cell differentiation and biological process this GO :0014841 and satellite cell proliferation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0034109 and homotypic cell-cell adhesion and biological process this GO :0042995 and cell projection and cellular component this GO :0043654 and recognition of apoptotic cell and biological process this GO :0048641 and regulation of skeletal muscle tissue development and biological process this GO :0051147 and regulation of muscle cell differentiation and biological process this GO :0055001 and muscle cell development and biological process, this GO :0004866: endopeptidase inhibitor activity, this GO :0004866: endopeptidase inhibitor activity and also this GO :0005515: protein binding, this GO :0005515: protein binding, multiple EGF-like-domains 10 |
| Identity | 29634 |
| Gene | MEGF10 |
| Long gene name | multiple EGF like domains 10 |
| Synonyms gene name | multiple EGF-like-domains 10 |
| Synonyms | KIAA1780 |
| Locus | 5q23, 2 |
| Discovery year | 2006-03-31 |
| GenBank acession | AK021631 |
| Entrez gene record | 84466 |
| Pubmed identfication | 11347906 |
| RefSeq identity | NM_032446 |
| Classification | Scavenger receptors |
| Havana BLAST/BLAT | OTTHUMG00000128984 |