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Merlin (Ser518) Antibody

Merlin (Ser518) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMerlin (Ser518) Antibody
Also known asMerlin (Ser518) Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMerlin (Ser518)
SpecificityThis is a highly specific antibody against Merlin (Ser518)
Modification(s)Phosphorylation
Modification site(s)Ser518
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range500-545/590
Subcellular location Cell membrane, Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human Merlin around the phosphorylation site of Ser518
Gene ID number4771
Swiss ProtP35240
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, May act as a membrane stabilizing protein, May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity, Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis, Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BANF, Merlin, Moesin-ezrin-radixin-like protein, NF2, Neurofibromin-2, SCH, Schwannomerlin, Schwannomin, ACN
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMerlin (Ser518)
Short nameMerlin (Ser518) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMerlin (Ser518) (Antibody to)
Alternative techniqueantibodies

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