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Midline 1 Antibody

Midline 1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMidline 1 Primary Polyclonal Antibody
Also known asMidline 1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMidline-1
SpecificityThis is a highly specific antibody against Midline-1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Midline-1/RNF59
Gene ID number4281
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects in MID1 are the cause of Opitz syndrome type I (OS-I), It also interacts with IGBP1 (Lymphocyte signaling protein A4), It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2, Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation, OS-I is an X-linked recessive disorder characterized by hypertelorism, OS-I mutations produce proteins with a decreased affinity for microtubules, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1, developmental delay and congenital heart defects, genital-urinary defects such as hypospadias in males and splayed labia in females, imperforate anus, lip-palate-laryngotracheal clefts, one B30, one COS domain, one fibronectin type-III domain and one RING-type zinc finger, 2/SPRY domain, Midline-1 (Tripartite motif-containing protein 18
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BBBG1, FXY, Finger on X and Y mouse homolog of antibody, GBBB 1, GBBB1, MID 1, MID-1, Mid1, Midin, Midline 1, Midline 1 Opitz/BBB syndrome, Midline 1 RING finger protein, Midline 1 ring finger, Midline-1, Midline1, OGS 1, OGS1, OS antibody, OSX, Putative transcription factor XPRF, RING finger protein 59, RNF 59, RNF59, TRI18, TRI18_HUMAN, TRIM 18, TRIM18, Tripartite mot containing protein 18, Tripartite mot protein TRIM18, Tripartite mot-containing protein 18, XPRF, ZNFXY, Zinc finger X and Y antibody, BBBG 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMidline 1
Short nameMidline 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMidline 1 (Antibody to)
Alternative techniqueantibodies
Identity 7095
Gene MID1
Long gene name midline 1
Synonyms OS FXY TRIM18 RNF59
Synonyms name Opitz/BBB syndrome
Locus Xp22
Discovery year 1997-12-12
GenBank acession Y13667
Pubmed identfication 9354791 9425238
Classification Tripartite motif containing Ring finger proteins Fibronectin type III domain containing
Havana BLAST/BLAT OTTHUMG00000021127
Locus Specific Databases Mental Retardation database

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