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MPZL2/EVA1 Antibody

MPZL2/EVA1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMPZL2/EVA1 Primary Polyclonal Antibody
Also known asMPZL2/EVA1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMPZL2/EVA1
SpecificityThis is a highly specific antibody against MPZL2/EVA1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MPZL2/EVA1
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression, It is highly homologous to the myelin protein zero and, Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis, Jul 2008], The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain, This gene is expressed in the thymus and in several epithelial structures early in embryogenesis, Two transcript variants encoding the same protein have been found for this gene, [provided by RefSeq, a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton, Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names EVA, EVA1, MPZL2, MPZL2 myelin protein zero like 2, MPZL2_HUMAN, Myelin protein zero like protein 2, epithelial V-like antigen, myelin protein zero-like 2, Epithelial V like antigen 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMPZL2/EVA1
Short nameMPZL2/EVA1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namemyelin protein zero-like 2/EVA1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target EVA and EVA1, MPZL2 and IDBG-631254 and ENSBTAG00000033510 and 540423, MPZL2 and IDBG-73587 and ENSG00000149573 and 10205, Mpzl2 and IDBG-159117 and ENSMUSG00000032092 and 14012, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0033077 and T cell differentiation in thymus and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, myelin protein zero-like 2
Identity 3496
Gene MPZL2
Long gene name myelin protein zero like 2
Synonyms gene EVA1
Synonyms gene name epithelial V-like antigen 1
Synonyms EVA
Locus 11q24
Discovery year 1999-11-22
GenBank acession AF275945
Entrez gene record 10205
Pubmed identfication 9585423
RefSeq identity NM_005797
Classification V-set domain containing
Havana BLAST/BLAT OTTHUMG00000166967

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