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MTMR2 Antibody

MTMR2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMTMR2 Primary Polyclonal Antibody
Also known asMTMR2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMTMR2
SpecificityThis is a highly specific antibody against MTMR2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MTMR2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3, MTMR2 interacts with MTMR5, MTMR3 and MTMR4 can either interact with each other or self associate, MTMR6 regulates the activity of the calcium-activated potassium channel 3, MTMR9 regulates the activity of MTMR7 and MTMR8, Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), They are protein tyrosine phosphatases that utilize inositol phospholipids, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization, as substrates, focally folded myelin sheaths and demyelination, rather than phosphoproteins, which is characterized by reduced nerve conduction velocities, 1, 5)P2, Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CMT4B1, KIAA1073, MTMR2, MTMR2_HUMAN, Myotubularin related protein 2, Myotubularin-related protein 2, CMT4B
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMTMR2
Short nameMTMR2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMTMR2 (Antibody to)
Alternative techniqueantibodies
Identity 7450
Gene MTMR2
Long gene name myotubularin related protein 2
Synonyms gene CMT4B
Synonyms KIAA1073
Synonyms name phosphatidylinositol-3-phosphatase phosphoinositide-3-phosphatase
Locus 11q21
Discovery year 1999-02-05
GenBank acession U58033
Entrez gene record 8898
Pubmed identfication 8640223 9736772
RefSeq identity NM_016156
Classification Phosphoinositide phosphatases Myotubularins
Havana BLAST/BLAT OTTHUMG00000153837
Locus Specific Databases Inherited Peripheral Neuropathies Mutation Database LRG_257

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