Name : MUL1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1834462424
| Long name | MUL1 Primary Polyclonal Antibody |
| Also known as | MUL1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MUL1 |
| Specificity | This is a highly specific antibody against MUL1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MUL1/RNF218 |
| Gene ID number | 79594 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugatin, Inhibits cell growth, Promotes mitochondrial fragmentation and influences mitochondrial localization, When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis, E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | C1orf166, E3 ubiquitin ligase, E3 ubiquitin protein ligase MUL1, GIDE, Growth inhibition and death E3 ligase, MAPL, MUL1, MUL1_HUMAN, MULAN, Mitochondrial anchored protein ligase, Mitochondrial ubiquitin ligase activator of NFKB 1, Putative NF kappa B activating protein 266, RING finger protein 218, RNF218, RP23-25C1, 10-002, E3 ubiquitin-protein ligase MUL1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MUL1 |
| Short name | MUL1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | mitochondrial E3 ubiquitin protein ligase 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | MUL1 and IDBG-645664 and ENSBTAG00000020850 and 508406, MUL1 and IDBG-92888 and ENSG00000090432 and 79594, Mul1 and IDBG-199848 and ENSMUSG00000041241 and 68350, identical protein binding, nuclei, this GO :0000266 and mitochondrial fission and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005777 and peroxisome and cellular component this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007005 and mitochondrion organization and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0010637 and negative regulation of mitochondrial fusion and biological process this GO :0016020 and membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016925 and protein sumoylation and biological process this GO :0019789 and SUMO ligase activity and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0031307 and integral component of mitochondrial outer membrane and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0033235 and positive regulation of protein sumoylation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0045824 and negative regulation of innate immune response and biological process this GO :0050689 and negative regulation of defense response to virus by host and biological process this GO :0050821 and protein stabilization and biological process this GO :0051646 and mitochondrion localization and biological process this GO :0051898 and negative regulation of protein kinase B signaling and biological process this GO :0060339 and negative regulation of type I interferon-mediated signaling pathway and biological process this GO :0071360 and cellular response to exogenous dsRNA and biological process this GO :0071650 and negative regulation of chemokine (C-C motif) ligand 5 production and biological process this GO :0090141 and positive regulation of mitochondrial fission and biological process this GO :1901028 and regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway and biological process, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0004871: signal transducer activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0019789: SUMO ligase activity and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0042802: identical protein binding, this GO :0004871: signal transducer activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0019789: SUMO ligase activity, this GO :0031625: ubiquitin protein ligase binding, this GO :0042802: identical protein binding, mitochondrial E3 ubiquitin protein ligase 1 |
| Identity | 25762 |
| Gene | MUL1 |
| Long gene name | mitochondrial E3 ubiquitin protein ligase 1 |
| Synonyms gene | C1orf166 |
| Synonyms gene name | chromosome 1 open reading frame 166 |
| Synonyms | FLJ12875 MULAN RNF218 MAPL GIDE |
| Synonyms name | ring finger protein 218 mitochondria-anchored protein ligase growth inhibition and death E3 ligase mitochondrial ubiquitin ligase activator of NFKB 1 |
| Locus | 1p36, 12 |
| Discovery year | 2005-07-19 |
| GenBank acession | BC014010 |
| Entrez gene record | 79594 |
| Pubmed identfication | 18591963 12761501 18213395 18207745 |
| RefSeq identity | NM_024544 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000002838 |