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NDEL1(Ser242) Antibody

NDEL1(Ser242) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNDEL1(Ser242) Primary Polyclonal Antibody
Also known asNDEL1(Ser242) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNDEL1 Ser242
SpecificityThis is a highly specific antibody against NDEL1 Ser242
Modification(s)Phosphorylation
Modification site(s)Ser242
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range230-260/345
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human NDEL1 around the phosphorylation site of Ser242
Gene ID number81565
Swiss ProtQ9GZM8
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also positively regulates the activity of the minus-end directed microtubule motor protein dynein, Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate, Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL, May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends, May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome, Plays a role, Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, in the regulation of neurite outgrowth, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome, together with DISC1, which instead requires NDE1, Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MITAP1, Mitosin-associated protein 1, NDE1L1, NDE2, NDEL1, NUDEL, Nuclear distribution protein nudE-like 1, Protein Nudel, EOPA
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNDEL1(Ser242)
Short nameNDEL1(Ser242) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNDEL1(Ser242) (Antibody to)
Alternative techniqueantibodies
Identity 17620
Gene NDEL1
Long gene name nudE neurodevelopment protein 1 like 1
Synonyms gene name nidulans)-like 1 , nidulans)-like 1 nudE nuclear distribution E homolog (A, nudE nuclear distribution gene E homolog (A
Synonyms NUDEL MITAP1 NDE1L1 NDE2
Locus 17p13, 1
Discovery year 2003-04-10
GenBank acession AF182078
Entrez gene record 81565
Pubmed identfication 11163260 11163259
RefSeq identity NM_030808
Havana BLAST/BLAT OTTHUMG00000108193

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