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NIMP Antibody

NIMP Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNIMP Primary Polyclonal Antibody
Also known asNIMP PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNIMP
SpecificityThis is a highly specific antibody against NIMP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NIMP/RTN4IP1
Gene ID number84816
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen -B and -C, NIMP (NOGO-interacting mitochondrial protein), NIMP is expressed in mitochondrial-rich tissue such as kidney, Nogo exists in three different splice forms, Nogo is expressed by oligodendrocytes but not by Schwann cells, Nogo-A, There are three isoforms of NIMP that are produced as a result of alternative splicing events, Through interaction with Nogo, also known as RTN4IP1 (Reticulon-4-interacting protein 1), and associates primarily with the endoplasmic reticulum, and inhibits the spreading of 3T3 fibroblasts, heart, induces collapse of growth cones of chick dorsal root ganglion cells, is a 396 amino acid mitochondrial protein that contains a C-terminal oxidoreductaselike domain and numerous sites for phosphorylation, it is likely that NIMP plays a role in Nogo-induced inhibition of neurite growth, skeletal muscle and specific regions within the nervous system, Appears to be a potent inhibitor of regeneration following spinal cord injury, Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NIMP, NIMP/RTN4IP1, NOGO interacting mitochondrial protein, NOGO-interacting mitochondrial protein, RT4I1_HUMAN, Reticulon 4 interacting protein 1, Reticulon 4 interacting protein 1, Reticulon-4-interacting protein 1, Rtn4ip1, mitochondrial, mitochondrial
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNIMP
Short nameNIMP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNIMP (Antibody to)
Alternative techniqueantibodies
Identity 18647
Gene RTN4IP1
Long gene name reticulon 4 interacting protein 1
Synonyms NIMP
Locus 6q21
Discovery year 2002-05-23
GenBank acession AF336861
Entrez gene record 84816
Havana BLAST/BLAT OTTHUMG00000015304

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