NLRP12 Antibody

NLRP12 Antibody size: 0.08 ml 199

Price 199

Size 0.08 ml

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Category	Antibody
Concentration	09% sodium azide, 4 with 0, In 1X PBS pH 7
Form	Antigen affinity purified
Conjugation	Unconjugated
Clone	Polyclonal antibody
Recognised antigen	NLRP12
Host animal	Rabbit (Oryctolagus cuniculus)
Clonality	Polyclonal (rabbit origin)
Species reactivity	Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications	ELISA, IHC, WB
Recommended dilutions	IHC (Paraffin): 1:10-1:50, Western blot: 1:1000
Notes	Titration of the NLRP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use	This NLRP12 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #	P59046
Purity	Antigen affinity
Description	Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined, The encoded protein, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes, which contains an N-terminal pyrin domain, This gene encodes a member of the CATERPILLER family of cytoplasmic proteins
Immunogen	A portion of amino acids 183-212 from the human protein was used as the immunogen for this NLRP12 antibody
Storage	Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the NLRP12 antibody and store frozen at -20 deg
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target	NLRP12
Short name	NLRP12 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	pyrin domain containing 12 (Antibody to), NLR family
Alternative technique	antibodies
Alternative to gene target	Cytoplasm, NLRP12 and IDBG-641617 and ENSBTAG00000038149 and 522018, NLRP12 and IDBG-67727 and ENSG00000142405 and 91662, Nlrp12 and IDBG-264083 and ENSMUSG00000078817 and 378425, cysteine-type endopeptidase activator activity involved in apoptotic process, pyrin domain containing 12, this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008588 and release of cytoplasmic sequestered NF-kappaB and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0009968 and negative regulation of signal transduction and biological process this GO :0031953 and negative regulation of protein autophosphorylation and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0036336 and dendritic cell migration and biological process this GO :0043122 and regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045345 and positive regulation of MHC class I biosynthetic process and biological process this GO :0045381 and regulation of interleukin-18 biosynthetic process and biological process this GO :0045409 and negative regulation of interleukin-6 biosynthetic process and biological process this GO :0045751 and negative regulation of Toll signaling pathway and biological process this GO :0050710 and negative regulation of cytokine secretion and biological process this GO :0050711 and negative regulation of interleukin-1 secretion and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :0071345 and cellular response to cytokine stimulus and biological process this GO :1901223 and negative regulation of NIK/NF-kappaB signaling and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0005524: ATP binding, this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process, NLR family
Identity	22938
Gene	NLRP12
Long gene name	NLR family pyrin domain containing 12
Synonyms gene	NALP12
Synonyms gene name	NACHT, leucine rich repeat and PYD containing 12
Synonyms	RNO2 PYPAF7 Monarch1 PAN6 CLR19, 3
Synonyms name	leucine rich repeat and pyrin domain containing 12 , nucleotide-binding oligomerization domain
Locus	19q13, 42
Discovery year	2003-10-28
GenBank acession	AY095146
Entrez gene record	91662
Pubmed identfication	12563287 12019269
RefSeq identity	NM_144687
Classification	NLR family Pyrin domain containing
Havana BLAST/BLAT	OTTHUMG00000060776
Locus Specific Databases	LRG_181

NLRP12 Antibody

NLRP12 Antibody size: 0.08 ml 199

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