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NMDAR2B (Tyr1336) Antibody

NMDAR2B (Tyr1336) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNMDAR2B (Tyr1336) Primary Polyclonal Antibody
Also known asNMDAR2B (Tyr1336) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNMDAR2B Tyr1336
Specificity This phosphorylation site is homologous to that of Tyr1336 in Mouse and Rat, This is a highly specific antibody against NMDAR2B Tyr1336
Modification(s)Phosphorylation
Modification site(s)Tyr1336
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1310-1360/1484
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1336
Gene ID number2904
Swiss ProtQ13224
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen In concert with DAPK1 at extrasynaptic sites, Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, Mediated by glycine, acts as a central mediator for stroke damage, resulting in an irreversible neuronal death (By similarity), NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GRIN2B, GluN2B, Glutamate [NMDA] receptor subunit epsilon-2, Glutamate receptor ionotropic, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NMDA 2B, NMDAR2B, NR2B, NR3, hNR3, MRD6
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNMDAR2B (Tyr1336)
Short nameNMDAR2B (Tyr1336) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNMDAR2B (Tyr1336) (Antibody to)
Alternative techniqueantibodies
Identity 4586
Gene GRIN2B
Long gene name glutamate ionotropic receptor NMDA type subunit 2B
Synonyms gene NMDAR2B
Synonyms gene name N-methyl D-aspartate 2B , glutamate receptor, ionotropic
Synonyms GluN2B
Locus 12p13, 1
Discovery year 1992-09-18
Entrez gene record 2904
Pubmed identfication 1350383
Classification Glutamate ionotropic receptor NMDA type subunits
Havana BLAST/BLAT OTTHUMG00000137373

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