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OTUB1 Antibody

OTUB1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameOTUB1 Primary Polyclonal Antibody
Also known asOTUB1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenOTUB1
SpecificityThis is a highly specific antibody against OTUB1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OTUB1
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Due to its interaction with GRAIL, Expressed as two isoforms (one of which is present throughout the body and the other of which is present only in lymphoid tissues), OTUB1 functions as a hydrolase that can remove ubiquitin residues from target proteins, OTUB1 interacts with GRAIL and, OTUB1 is an important regulator of immune responses in secondary lymphoid organs, a phenomenon that occurs when T-cells are rendered unresponsive to their cognate antigens, plays a role in the regulation and the induction of T-cell anergy, thereby preventing protein degradation and playing an important role in protein turnover, via this interaction, OTUB1 is a 271 amino acid protein that contains one OTU (ovarian tumor) domain and belongs to the OTU family of predicted cysteine proteases
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names OTB1, OTU domain containing ubiquitin aldehyde binding protein 1, OTU domain-containing ubiquitin aldehyde-binding protein 1, OTU1, OTUB1_HUMAN, Otub1, Otubain 1, Otubain-1, Ubiquitin specic processing protease OTUB1, Ubiquitin thioesterase OTUB1, Ubiquitin-specic-processing protease OTUB1, hOTU1, Deubiquitinating enzyme OTUB1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetOTUB1
Short nameOTUB1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameOTUB1 (Antibody to)
Alternative techniqueantibodies
Identity 23077
Gene OTUB1
Long gene name OTU deubiquitinase, ubiquitin aldehyde binding 1
Synonyms gene name OTU domain, ubiquitin aldehyde binding 1
Synonyms FLJ20113 FLJ40710
Locus 11q13, 1
Discovery year 2003-12-12
GenBank acession AY177200
Entrez gene record 55611
Pubmed identfication 12704427 19383985
RefSeq identity NM_017670
Classification OTU domain containing
Havana BLAST/BLAT OTTHUMG00000167786

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