Name : p130 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :354
SKU : GEN7081390833
| Long name | p130 Primary Polyclonal Antibody |
| Also known as | p130 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | p130 |
| Specificity | This is a highly specific antibody against p130 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | Synthetic peptide |
| Gene ID number | 5934 |
| Swiss Prot | Q08999 |
| Tested Applications | WB |
| Recommended dilutions | 000), WB (1:2 |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binds to and may be involved in the transforming capacity of the adenovirus E1A protein, Binds to cyclins A and E, Controls histone H4 'Lys-20' trimethylation, Directly involved in heterochromatin formation by maintaining overall chromatin structure and, May act as a tumor suppressor, Potent inhibitor of E2F-mediated trans-activation, Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters, Recruits and targets histone methyltransferases KMT5B and KMT5C, associates preferentially with E2F5, in particular, leading to epigenetic transcriptional repression, that of constitutive heterochromatin by stabilizing histone methylation, Key regulator of entry into cell division |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 130 kDa retinoblastoma-associated protein, P130, RBL2, RBR-2, Retinoblastoma-like protein 2, Retinoblastoma-related protein 2, pRb2, Rb2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | p130 |
| Short name | p130 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | p130 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 15608 |
| Gene | NOLC1 |
| Long gene name | nucleolar and coiled-body phosphoprotein 1 |
| Synonyms | P130 KIAA0035 NOPP140 NOPP130 |
| Locus | 10q24, 32 |
| Discovery year | 2001-05-17 |
| GenBank acession | Z34289 |
| Entrez gene record | 9221 |
| Pubmed identfication | 7657714 10567578 |
| RefSeq identity | NM_004741 |
| Havana BLAST/BLAT | OTTHUMG00000018944 |