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PA26 Antibody

PA26 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePA26 Primary Polyclonal Antibody
Also known asPA26 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPA26
SpecificityThis is a highly specific antibody against PA26
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SESN1/PA26
Gene ID number27244
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A related DNA-damage inducible gene, An additional GADD related gene, GADD 34 synergizes with GADD 45 or GADD 153 in suppressing cell growth, GADD 45 stimulates DNA excision repair in vitro and inhibits entry of cells into S phase, PA26, PA26-T2 and PA26-T3, PEG-3 (progression elevated gene-3) shares significant homology with GADD 34 and is inducible by DNA damage, The p53 tumor suppressor is required for one such G1 checkpoint and functions to upregulate expression of GADD 45 and the mitotic inhibitory protein p21, Three isoforms of PA26 have been identified as PA26-T1, and it apparently acts in concert with GADD 153 in inducing growth arrest, is a possible target of p53, presumably to allow time for DNA repair prior to entry into S and M phase, respectively, Cell cycle progression is subject to arrest at G1 and G2 checkpoints in response to DNA damage
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names PA26, SESN1_HUMAN, SEST1, Sestrin-1, p53 regulated protein PA26, p53-regulated protein PA26, sesn1, sestrin 1, p53 regulated PA26 nuclear protein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPA26
Short namePA26 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePA26 (Antibody to)
Alternative techniqueantibodies
Identity 21595
Gene SESN1
Long gene name sestrin 1
Synonyms SEST1 PA26
Locus 6q21
Discovery year 2003-09-03
GenBank acession AF033120
Entrez gene record 27244
Pubmed identfication 9926927 7938006
RefSeq identity NM_014454
Havana BLAST/BLAT OTTHUMG00000015338

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