Name : PCDHB12 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2451818128
| Long name | PCDHB12 Primary Polyclonal Antibody |
| Also known as | PCDHB12 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | PCDHB12 |
| Specificity | This is a highly specific antibody against PCDHB12 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PCDHB12 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | As a result, Localized to the cell membrane, PCDHB12 (Protocadherin beta 12) is a 795 amino acid protein that is one of 16 proteins in the protocadherin beta cluster, PCDHB12 is a single-pass type I membrane protein that contains six cadherin domains, PCDHB12 may participate in the establishment and maintenance of specific neuronal connections in the brain, There are three protocadherin gene clusters, Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, all of which contain multiple tandemly arranged genes, beta and gamma, designated alpha, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein, members of the beta cluster (such as PCDHB12) do not use constant-region exons to produce mRNAs, Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | PCDBC_HUMAN, PCDHB 12, PCDHB12, PCDH beta12 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PCDHB12 |
| Short name | PCDHB12 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | protocadherin b 12 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | PCDHB12 and IDBG-50135 and ENSG00000120328 and 56124, Plasma membranes, calcium ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007399 and nervous system development and biological process this GO :0016020 and membrane and cellular component, this GO :0005509: calcium ion binding, this GO :0005509: calcium ion binding, protocadherin beta 12 |
| Identity | 8683 |
| Gene | PCDHB12 |
| Long gene name | protocadherin beta 12 |
| Synonyms | PCDH-BETA12 |
| Locus | 5q31, 3 |
| Discovery year | 2000-06-28 |
| GenBank acession | AF152491 |
| Entrez gene record | 56124 |
| Pubmed identfication | 10380929 |
| RefSeq identity | NM_018932 |
| Classification | Clustered protocadherins |
| Havana BLAST/BLAT | OTTHUMG00000129620 |