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PCDHB6 Antibody

PCDHB6 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePCDHB6 Primary Polyclonal Antibody
Also known asPCDHB6 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPCDHB6
SpecificityThis is a highly specific antibody against PCDHB6
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PCDHB6
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen As a result, PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain, There are three protocadherin gene clusters, Unlike most protocadherin-beta proteins, Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, all of which contain multiple tandemly arranged genes, beta and gamma, designated alpha, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs, suggesting a role in signal transduction cascade events, Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names PCDHB 6, Protocadherin beta 6, #65279, &, PCDH beta 6, PCDH beta6
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPCDHB6
Short namePCDHB6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameprotocadherin b 6 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target PCDHB6 and IDBG-49974 and ENSG00000113211 and 56130, PCDHB6 and IDBG-648650 and ENSBTAG00000047478 and 786512, Pcdhb13 and IDBG-139928 and ENSMUSG00000047307 and 93884, Plasma membranes, calcium ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007399 and nervous system development and biological process this GO :0007416 and synapse assembly and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016339 and calcium-dependent cell-cell adhesion and biological process, this GO :0005509: calcium ion binding, this GO :0005509: calcium ion binding, protocadherin beta 6
Identity 8691
Gene PCDHB6
Long gene name protocadherin beta 6
Synonyms PCDH-BETA6
Locus 5q31, 3
Discovery year 2000-06-28
GenBank acession AF152499
Entrez gene record 56130
Pubmed identfication 10380929
RefSeq identity NM_018939
Classification Clustered protocadherins
Havana BLAST/BLAT OTTHUMG00000129623

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