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PLCG2(Tyr1217) Antibody

PLCG2(Tyr1217) Antibody size: 0.1ml 281

Price 281
Size 0.1ml
Long namePLCG2(Tyr1217) Primary Polyclonal Antibody
Also known asPLCG2(Tyr1217) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPLCG2Tyr1217
SpecificityThis is a highly specific antibody against PLCG2Tyr1217
Modification(s)Phosphorylation
Modification site(s)Tyr1217
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PLC gamma 2 around the phosphorylation site of Tyr1217
Gene ID number5336
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A number of these enzymes have specificity for phosphoinositides, C beta is regulated by heterotrimeric G protein coupled receptors, Of the phosphoinositide specific phospholipase C enzymes, SH2 and SH3, The C gamma 1 and C gamma 2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, while the closely related C gamma 1 and C gamma 2 enzymes are controlled by receptor tyrosine kinases, Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water soluble phosphorylated derivatives of the lipid head groups
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2, EC 3, PLC Î, PLC 2, PLC IV, PLC gamma 2, PLC gamma 2/PLCG2Tyr1217, PLCG2, PLCG2_HUMAN, Phosphoinositide phospholipase C, Phospholipase C, Phospholipase C gamma 2, gamma 2 phosphatidylinositol specic, ³, 1, 2Tyr1217, 4, 11, PLCG2phospho Y1217
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPLCG2(Tyr1217)
Short namePLCG2(Tyr1217) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name gamma 2 (phosphatidylinositol-specific)(Tyr1217) (Antibody to), phospholipase C
Alternative techniqueantibodies
Alternative to gene target APLAID and FCAS3 and PLC-gamma-2 and PLC-IV, PLCG2 and IDBG-43723 and ENSG00000197943 and 5336, PLCG2 and IDBG-629513 and ENSBTAG00000002103 and 100337091, Plasma membranes, Plcg2 and IDBG-195070 and ENSMUSG00000034330 and 234779, gamma 2 (phosphatidylinositol-specific), phosphoric diester hydrolase activity, this GO :0002316 and follicular B cell differentiation and biological process this GO :0004435 and phosphatidylinositol phospholipase C activity and molecular function this GO :0004629 and phospholipase C activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006661 and phosphatidylinositol biosynthetic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008081 and phosphoric diester hydrolase activity and molecular function this GO :0009395 and phospholipid catabolic process and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0019722 and calcium-mediated signaling and biological process this GO :0030168 and platelet activation and biological process this GO :0030183 and B cell differentiation and biological process this GO :0032237 and activation of store-operated calcium channel activity and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032959 and inositol trisphosphate biosynthetic process and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0043069 and negative regulation of programmed cell death and biological process this GO :0043647 and inositol phosphate metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004435: phosphatidylinositol phospholipase C activity, this GO :0004435: phosphatidylinositol phospholipase C activity and also this GO :0004629: phospholipase C activity and also this GO :0004871: signal transducer activity and also this GO :0005515: protein binding and also this GO :0008081: phosphoric diester hydrolase activity, this GO :0004629: phospholipase C activity, this GO :0004871: signal transducer activity, this GO :0005515: protein binding, this GO :0008081: phosphoric diester hydrolase activity, phospholipase C
Identity 9066
Gene PLCG2
Long gene name phospholipase C gamma 2
Synonyms gene name gamma 2 (phosphatidylinositol-specific) , phospholipase C
Locus 16q24, 1
Discovery year 1994-05-16
Entrez gene record 5336
Pubmed identfication 7835906
Classification Phospholipases SH2 domain containing C2 domain containing phospholipases
Havana BLAST/BLAT OTTHUMG00000176532
Locus Specific Databases LRG_376

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