Name : PLCG2(Tyr1217) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN9443504945
| Long name | PLCG2(Tyr1217) Primary Polyclonal Antibody |
| Also known as | PLCG2(Tyr1217) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | PLCG2Tyr1217 |
| Specificity | This is a highly specific antibody against PLCG2Tyr1217 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Tyr1217 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human PLC gamma 2 around the phosphorylation site of Tyr1217 |
| Gene ID number | 5336 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | A number of these enzymes have specificity for phosphoinositides, C beta is regulated by heterotrimeric G protein coupled receptors, Of the phosphoinositide specific phospholipase C enzymes, SH2 and SH3, The C gamma 1 and C gamma 2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, while the closely related C gamma 1 and C gamma 2 enzymes are controlled by receptor tyrosine kinases, Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water soluble phosphorylated derivatives of the lipid head groups |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2, EC 3, PLC Î, PLC 2, PLC IV, PLC gamma 2, PLC gamma 2/PLCG2Tyr1217, PLCG2, PLCG2_HUMAN, Phosphoinositide phospholipase C, Phospholipase C, Phospholipase C gamma 2, gamma 2 phosphatidylinositol specic, ³, 1, 2Tyr1217, 4, 11, PLCG2phospho Y1217 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PLCG2(Tyr1217) |
| Short name | PLCG2(Tyr1217) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | gamma 2 (phosphatidylinositol-specific)(Tyr1217) (Antibody to), phospholipase C |
| Alternative technique | antibodies |
| Alternative to gene target | APLAID and FCAS3 and PLC-gamma-2 and PLC-IV, PLCG2 and IDBG-43723 and ENSG00000197943 and 5336, PLCG2 and IDBG-629513 and ENSBTAG00000002103 and 100337091, Plasma membranes, Plcg2 and IDBG-195070 and ENSMUSG00000034330 and 234779, gamma 2 (phosphatidylinositol-specific), phosphoric diester hydrolase activity, this GO :0002316 and follicular B cell differentiation and biological process this GO :0004435 and phosphatidylinositol phospholipase C activity and molecular function this GO :0004629 and phospholipase C activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006661 and phosphatidylinositol biosynthetic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008081 and phosphoric diester hydrolase activity and molecular function this GO :0009395 and phospholipid catabolic process and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0019722 and calcium-mediated signaling and biological process this GO :0030168 and platelet activation and biological process this GO :0030183 and B cell differentiation and biological process this GO :0032237 and activation of store-operated calcium channel activity and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032959 and inositol trisphosphate biosynthetic process and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0043069 and negative regulation of programmed cell death and biological process this GO :0043647 and inositol phosphate metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004435: phosphatidylinositol phospholipase C activity, this GO :0004435: phosphatidylinositol phospholipase C activity and also this GO :0004629: phospholipase C activity and also this GO :0004871: signal transducer activity and also this GO :0005515: protein binding and also this GO :0008081: phosphoric diester hydrolase activity, this GO :0004629: phospholipase C activity, this GO :0004871: signal transducer activity, this GO :0005515: protein binding, this GO :0008081: phosphoric diester hydrolase activity, phospholipase C |
| Identity | 9066 |
| Gene | PLCG2 |
| Long gene name | phospholipase C gamma 2 |
| Synonyms gene name | gamma 2 (phosphatidylinositol-specific) , phospholipase C |
| Locus | 16q24, 1 |
| Discovery year | 1994-05-16 |
| Entrez gene record | 5336 |
| Pubmed identfication | 7835906 |
| Classification | Phospholipases SH2 domain containing C2 domain containing phospholipases |
| Havana BLAST/BLAT | OTTHUMG00000176532 |
| Locus Specific Databases | LRG_376 |