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PSAP Antibody

PSAP Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePSAP Primary Polyclonal Antibody
Also known asPSAP PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPSAP/PAP
SpecificityThis is a highly specific antibody against PSAP/PAP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range144-194/524
Subcellular locationSecreted
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PSAP
Gene ID number5660
Swiss ProtP07602
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen GM1 gangliosides by beta-galactosidase (EC 3, GPR37 and GPR37L1, Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases, Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3, Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3, Saposins are specific low-molecular mass non-enzymic proteins, rather than by solubilizing the substrate, these effects are mediated by its G-protein-coupled receptors, they participate in the lysosomal degradation of sphingolipids, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling, which takes place by the sequential action of specific hydrolases, 1, 1, 1, 1, 1, 1, 12), 2, 2, 2, 2, 22), 23) and globotriaosylceramide by alpha-galactosidase A (EC 3, 4, 45) and galactosylceramide by beta-galactosylceramidase (EC 3, 46), 6, 8), Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names PSAP, Proactivator polypeptide, Prosaposin, SAP1, GLBA
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPSAP
Short namePSAP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePSAP (Antibody to)
Alternative techniqueantibodies
Identity 9498
Gene PSAP
Long gene name prosaposin
Synonyms gene SAP1 GLBA
Synonyms gene name sphingolipid activator protein-1
Synonyms name variant Gaucher disease and variant metachromatic leukodystrophy
Locus 10q22, 1
Discovery year 1986-01-01
GenBank acession BC004275
Entrez gene record 5660
Pubmed identfication 2717620
RefSeq identity NM_002778
Classification Endogenous ligands
Havana BLAST/BLAT OTTHUMG00000018429

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