Name : PSD-95 Antibody
Supplier : NJS POLY
Price :406
SKU : GEN1603834171
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | PSD-95 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Optimal dilution of the PSD95 antibody should be determined by the researcher |
| Intented use | This PSD95 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P78352 |
| Purity | Antigen affinity |
| Description | DLG2, DLG4 can heteromultimerize with another MAGUK protein, DLG4 can orchestrate synaptic development and it has a role in synapse stabilization and plasticity, It is a member of the membrane-associated guanylate kinase (MAGUK) family, Overexpression of DLG4 in hippocampal neurons could drive maturation of glutamatergic synapses, These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, This gene is mapped to 17p13, Ubiquitination of DLG4 through an MDM2-mediated pathway can regulate AMPA receptor surface expression during synaptic plasticity, also known as PSD95 or SAP-90, and associated signaling proteins, and is recruited into NMDA receptor and potassium channel clusters, ion channels, is a protein that in humans is encoded by the DLG4 gene, 1, DLG4 (Discs large homolog 4) |
| Immunogen | Amino acids 581-724 of human PSD95 were used as the immunogen for the PSD95 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PSD95 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | Cytoplasmic |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | PSD |
| Short name | PSD-95 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | PSD-95 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9507 |
| Gene | PSD |
| Long gene name | pleckstrin and Sec7 domain containing |
| Synonyms gene name | pleckstrin and Sec7 domain protein |
| Synonyms | KIAA2011 TYL PSD1 EFA6A EFA6 |
| Locus | 10q24, 32 |
| Discovery year | 1997-08-18 |
| GenBank acession | X99688 |
| Entrez gene record | 5662 |
| Pubmed identfication | 9417912 |
| Classification | Pleckstrin homology domain containing |
| Havana BLAST/BLAT | OTTHUMG00000018954 |