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RCC1 (Ser11) Antibody

RCC1 (Ser11) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRCC1 (Ser11) Primary Polyclonal Antibody
Also known asRCC1 (Ser11) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRCC1 Ser11
SpecificityThis is a highly specific antibody against RCC1 Ser11
Modification(s)Phosphorylation
Modification site(s)Ser11
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human RCC1 around the phosphorylation site of Ser11
Gene ID number1104
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen RCC1, RanGTP localization has been proposed to result from the association of Ran's GDP/GTP exchange factor, The latter functions rely on the presence of high local concentrations of GTP bound Ran near mitotic chromatin, and, but Ran is shown here to bind directly to chromatin in two modes, either dependent or independent of RCC1, to increase the affinity of chromatin for NE membranes, where bound, with chromatin , Ran GTPase plays important roles in nucleocytoplasmic transport in interphase and in both spindle formation and nuclear envelope (NE) assembly during mitosis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CHC 1, CHC1, Chromosome condensation 1, Chromosome condensation protein 1, Guanine nucleotide releasing protein, HERC2, RCC 1, RCC1 I, RCC1_HUMAN, Ran GEF, RanGEF, Regulator of chromosome condensation, Regulator of chromosome condensation 1, SHEP1, Cell cycle regulatory protein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRCC1 (Ser11)
Short nameRCC1 (Ser11) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRCC1 (Ser11) (Antibody to)
Alternative techniqueantibodies
Identity 1913
Gene RCC1
Long gene name regulator of chromosome condensation 1
Synonyms gene CHC1
Synonyms gene name chromosome condensation 1
Locus 1p35, 3
Discovery year 1986-01-01
GenBank acession X12654
Entrez gene record 1104
Pubmed identfication 7851910
RefSeq identity NM_001269
Havana BLAST/BLAT OTTHUMG00000003645

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