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Rictor (Thr1135) Antibody

Rictor (Thr1135) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRictor (Thr1135) Primary Polyclonal Antibody
Also known asRictor (Thr1135) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRictor Thr1135
Specificity This phosphorylation site is homologous to that of Thr1135 in Mouse and Thr1120 in Rat, This is a highly specific antibody against Rictor Thr1135
Modification(s)Phosphorylation
Modification site(s)Thr1135
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1100-1150/1732
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human Rictor around the phosphorylation site of Thr1135
Gene ID number253260
Swiss ProtQ6R327
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Plays an essential role in embryonic growth and development, but, in contrast to mTORC1, mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657', mTORC2 is activated by growth factors, mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, mTORC2 promotes the serum-induced formation of stress-fibers or F-actin, mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422', mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors, seems to be nutrient-insensitive, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation, which regulates cell growth and survival in response to hormonal signals, Subunit of mTORC2
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AVO3, AVO3 homolog, KIAA1999, RICTOR, Rapamycin-insensitive companion of mTOR, hAVO3, PIA
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRictor (Thr1135)
Short nameRictor (Thr1135) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRictor (Thr1135) (Antibody to)
Alternative techniqueantibodies

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