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RNF142 Antibody

RNF142 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRNF142 Primary Polyclonal Antibody
Also known asRNF142 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRNF142
SpecificityThis is a highly specific antibody against RNF142
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SH3MD2/RNF142
Gene ID number57630
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen MAP2K7 and JNKs (MAPK8 and MAPK9), SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane, The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, There are two named isoforms, This gene encodes a protein containing an N-terminus RING-finger, Via the RING-finger, Within a signaling complex, and a region implicated in binding of the Rho GTPase Rac, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis, facilitating the formation of a functional signaling module, four SH3 domains, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network, SH3MD2 acts as a scaffold protein
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names POSH, Plenty of SH3s, RNF 142, RNF142, Ring finger protein 142, SH3 domain containing RING finger protein 1, SH3 domain containing ring finger 1, SH3 multiple domains 2, SH3MD2, SH3RF1, Plenty of SH3 domains
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRNF142
Short nameRNF142 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRNF142 (Antibody to)
Alternative techniqueantibodies
Identity 17650
Gene SH3RF1
Long gene name SH3 domain containing ring finger 1
Synonyms gene SH3MD2
Synonyms gene name SH3 multiple domains 2
Synonyms POSH RNF142 KIAA1494
Synonyms name plenty of SH3 domains
Locus 4q32, 3-q33
Discovery year 2003-12-01
GenBank acession BC033203
Entrez gene record 57630
Pubmed identfication 9482736
RefSeq identity NM_020870
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000161010

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