Filters

RORG Antibody

RORG Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRORG Primary Polyclonal Antibody
Also known asRORG PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRORG
SpecificityThis is a highly specific antibody against RORG
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range440-490/518
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RORG
Gene ID number6097
Swiss ProtP51449
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ARNTL/BMAL1 and NR1D1 in peripheral tissues and in a tissue-selective manner, CRY1 and NR1D1 itself, Competes with NR1D1 for binding to their shared DNA response element on some clock genes such as ARNTL/BMAL1, Considered to have intrinsic transcriptional activity, Controls adipogenesis as well as adipocyte size and modulates insulin sensitivity in obesity, In liver, Involved in the regulation of the rhythmic expression of genes involved in glucose and lipid metabolism, Key regulator of cellular differentiation, Negative regulator of adipocyte differentiation through the regulation of early phase genes expression, Recruits distinct combinations of cofactors to target gene regulatory regions to modulate their transcriptional expression, Regulates the circadian expression of clock genes such as CRY1, Therefore influences the period length and stability of the clock, depending on the tissue, enhancing or repressing the transcriptional activity, has specific and redundant functions with RORA as positive or negative modulator of expression of genes encoding phase I and Phase II proteins involved in the metabolism of lipids, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), immunity, including PLIN2 and AVPR1A, leading to the circadian pattern of clock genes expression, peripheral circadian rhythm as well as lipid, respectively, resulting in NR1D1-mediated repression or RORC-mediated activation of the expression, steroid, steroids and xenobiotics, such as MMP3, such as SULT1E1, time and promoter contexts, xenobiotics and glucose metabolism, Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NR1F3, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, RAR-related orphan receptor C, RORC, RORG, RZR-GAMMA, RZRG, Retinoid-related orphan receptor-gamma, TOR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRORG
Short nameRORG Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRORG (Antibody to)
Alternative techniqueantibodies
Identity 10260
Gene RORC
Long gene name RAR related orphan receptor C
Synonyms gene name RAR-related orphan receptor C
Synonyms RZRG RORG NR1F3 TOR
Locus 1q21
Discovery year 1995-04-13
GenBank acession U16997
Pubmed identfication 7811290
Classification Nuclear hormone receptors
Havana BLAST/BLAT OTTHUMG00000013053

Similar products

Subscribe to our Newsletter