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RUNX2 Antibody

RUNX2 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenRUNX2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, WB, IHC
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Western blot: 1:1000
NotesTitration of the RUNX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis RUNX2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q13950
PurityAntigen affinity
Description 5'-PYGPYGGT-3', CBF binds to the core site, Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification, IL-3 and GM-CSF promoters, In osteoblasts, Inhibits KAT6B-dependent transcriptional activation, LCK, T-cell receptor enhancers, [UniProt], alpha 1(I) collagen, bone sialoprotein, including murine leukemia virus, of a number of enhancers and promoters, osteocalcin, osteopontin, polyomavirus enhancer, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity), RUNX2 is a transcription factor involved in osteoblastic differentiation and skeletal morphogenesis
ImmunogenA portion of amino acids 445-474 from the human protein was used as the immunogen for this RUNX2 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the RUNX2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetRUNX2
Short nameRUNX2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRUNX2 (Antibody to)
Alternative techniqueantibodies
Identity 10472
Gene RUNX2
Long gene name runt related transcription factor 2
Synonyms gene CCD CBFA1 CCD1
Synonyms gene name runt-related transcription factor 2
Synonyms AML3 PEBP2A1 PEBP2aA1
Locus 6p21, 1
Discovery year 1994-11-02
GenBank acession AF001450
Entrez gene record 860
Pubmed identfication 7835892
RefSeq identity NM_004348
Havana BLAST/BLAT OTTHUMG00000014774

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