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RUNX2(Ser451) Antibody

RUNX2(Ser451) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRUNX2(Ser451) Primary Polyclonal Antibody
Also known asRUNX2(Ser451) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRUNX2 Ser451
SpecificityThis is a highly specific antibody against RUNX2 Ser451
Modification(s)Phosphorylation
Modification site(s)Ser451
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human RUNX2 around the phosphorylation site of Ser451
Gene ID number860
Swiss ProtQ13950
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 5'-PYGPYGGT-3', CBF binds to the core site, Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification, IL-3 and GM-CSF promoters, In osteoblasts, Inhibits KAT6B-dependent transcriptional activation, LCK, T-cell receptor enhancers, alpha 1(I) collagen, bone sialoprotein, including murine leukemia virus, of a number of enhancers and promoters, osteocalcin, osteopontin, polyomavirus enhancer, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity), Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AML3, Acute myeloid leukemia 3 protein, CBF-alpha-1, CBFA1, CCD1, CLCD, Core-binding factor subunit alpha-1, OSF-2, OSF2, Oncogene AML-3, Osteoblast-specific transcription factor 2, PEA2-alpha A, PEA2aA, PEBP2-alpha A, PEBP2A, PEBP2aA, Polyomavirus enhancer-binding protein 2 alpha A subunit, RUNX2, Runt-related transcription factor 2, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit, CCD
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRUNX2(Ser451)
Short nameRUNX2(Ser451) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRUNX2(Ser451) (Antibody to)
Alternative techniqueantibodies
Identity 10472
Gene RUNX2
Long gene name runt related transcription factor 2
Synonyms gene CCD CBFA1 CCD1
Synonyms gene name runt-related transcription factor 2
Synonyms AML3 PEBP2A1 PEBP2aA1
Locus 6p21, 1
Discovery year 1994-11-02
GenBank acession AF001450
Entrez gene record 860
Pubmed identfication 7835892
RefSeq identity NM_004348
Havana BLAST/BLAT OTTHUMG00000014774

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