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SKP2 Antibody

SKP2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSKP2 Primary Polyclonal Antibody
Also known asSKP2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSKP2
SpecificityThis is a highly specific antibody against SKP2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range383-424/424
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Skp2
Gene ID number6502
Swiss ProtQ13309
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CDK9, CDT1, Degradation of CDKN1B/p27kip also requires CKS1, Degradation of TAL1 also requires STUB1, FOXO1, KMT2A/MLL1, Promotes ubiquitination and destruction of CDH1 in a CK1-Dependent Manner, RAG2, RBL2, Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2, Recognizes target proteins ORC1, Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition, TOB1 and TAL1, UBP43, and probably MYC, signal transduction and transcription, thereby regulating cell migration, Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Cyclin-A/CDK2-associated protein p45, F-box protein Skp2, F-box/LRR-repeat protein 1, FBL1, FBXL1, FLB1, S-phase kinase-associated protein 2, SKP2, p45skp2, p45
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSKP2
Short nameSKP2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSKP2 (Antibody to)
Alternative techniqueantibodies
Identity 10901
Gene SKP2
Long gene name S-phase kinase associated protein 2
Synonyms gene name E3 ubiquitin protein ligase , S-phase kinase-associated protein 2 (p45) S-phase kinase-associated protein 2
Synonyms FBXL1 FBL1 p45
Locus 5p13, 2
Discovery year 1995-12-18
GenBank acession U33761
Entrez gene record 6502
Pubmed identfication 8646875
RefSeq identity NM_005983
Classification F-box and leucine rich repeat proteins
Havana BLAST/BLAT OTTHUMG00000131106

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