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SLAP Antibody

SLAP Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSLAP Primary Polyclonal Antibody
Also known asSLAP PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSLAP
SpecificityThis is a highly specific antibody against SLAP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLAP
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 3BP1 has been identified as a protein with a high affinity proline-rich binding site for the SH3 domain of c-Abl p120, A similar putative adapter protein, Deletion or mutation of SH3 domains generally activate the transforming potential of nonreceptor tyrosine kinases, In general, SH3 domains are often accompanied by SH2 domains of 100 amino acids, Slap contains a single SH2 and SH3 domain that exhibits homology with those from members of the Src kinase family, The N- and C-termini, The functions of SH3 domains are not as well defined, and in small adapter proteins, are unique, as in the nonreceptor protein-tyrosine kinases and phospholipase C-? within structural proteins, designated Slap, for Src-like adapter protein, frequently linking activated growth factors to putative signal transduction proteins, has been cloned, however, it exists in association with catalytic domains, such as Crk and GRB2, such as spectrin or Myosin, suggesting that SH3 mediates negative regulation of an intrinsic transforming activity, which bind to tyrosine-phosphorylated regions of target proteins, The Src homology 3 (SH3) region is a small protein domain of approximately 60 amino acids present in a large group of proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names SLA, SLA 1, SLA1, SLAP, SLAP 1, SLAP-1, SLAP1, SLAP1_HUMAN, SRC-like-adapter, Src like adapter, Src like adapter protein 1, Src like adaptor, Src-like-adapter protein 1, hSLAP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSLAP
Short nameSLAP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSLAP (Antibody to)
Alternative techniqueantibodies
Identity 16643
Gene SLMAP
Long gene name sarcolemma associated protein
Synonyms SLAP KIAA1601
Synonyms name Sarcolemmal-associated protein
Locus 3p14, 3
Discovery year 2001-12-03
GenBank acession AF100750
Entrez gene record 7871
Pubmed identfication 9405447 11042152
RefSeq identity NM_007159
Classification STRIPAK complex
Havana BLAST/BLAT OTTHUMG00000133764

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