Name : Tgfbr1 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN6244894037
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Tgfbr1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications | ELISA, WB |
| Recommended dilutions | Western blot: 1:1000 |
| Notes | Titration of the Tgfbr1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This Tgfbr1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q64729 |
| Purity | Antigen affinity |
| Description | Receptor for TGF-beta, Type II receptors phosphorylate and activate type I receptors which autophosphorylate, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases, then bind and activate SMAD transcriptional regulators, On ligand binding |
| Immunogen | A portion of amino acids 141-169 from the mouse protein was used as the immunogen for this Tgfbr1 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Tgfbr1 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Tgfbr1 |
| Short name | Tgfbr1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | b receptor 1 (Antibody to), transforming growth factor |
| Alternative technique | antibodies |
| Identity | 11772 |
| Gene | TGFBR1 |
| Long gene name | transforming growth factor beta receptor 1 |
| Synonyms gene | MSSE ESS1 |
| Synonyms gene name | multiple self-healing squamous epithelioma transforming growth factor beta receptor I |
| Synonyms | ALK-5 ACVRLK4 ALK5 |
| Synonyms name | 53kDa , activin A receptor type II-like kinase |
| Locus | 9q22, 33 |
| Discovery year | 1993-09-30 |
| Entrez gene record | 7046 |
| Pubmed identfication | 1319842 8530052 21358634 |
| Classification | Type 1 receptor serine/threonine kinases |
| Havana BLAST/BLAT | OTTHUMG00000020353 |
| Locus Specific Databases | Belgium , Ghent, LOVD - Center for Medical Genetics |