Filters

TRP12 Antibody

TRP12 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTRP12 Primary Polyclonal Antibody
Also known asTRP12 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTRP12
SpecificityThis is a highly specific antibody against TRP12
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range310-360/871
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRPV4
Gene ID number59341
Swiss ProtQ9HBA0
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification, Acts as a regulator of intracellular Ca(2+) in synoviocytes, Also activated by low pH, Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism, Increase of intracellular Ca(2+) potentiates currents, Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12, Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers, citrate and phorbol esters, 13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8, Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BCYM3, CMT2C, HMSN2C, OTRPC4, Osm-9-like TRP channel 4, SPSMA, SSQTL1, TRP12, Transient receptor potential cation channel subfamily V member 4, Transient receptor potential protein 12, TrpV4, VR-OAC, VRL-2, VRL2, VROAC, Vanilloid receptor-like channel 2, Vanilloid receptor-like protein 2, Vanilloid receptor-related osmotically-activated channel, SMAL
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTRP12
Short nameTRP12 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTRP12 (Antibody to)
Alternative techniqueantibodies
Identity 18083
Gene TRPV4
Long gene name transient receptor potential cation channel subfamily V member 4
Synonyms gene name member 4 , subfamily V, transient receptor potential cation channel
Synonyms OTRPC4 TRP12 VROAC VRL-2 VR-OAC CMT2C
Synonyms name osmosensitive transient receptor potential channel 4
Locus 12q24, 11
Discovery year 2002-01-29
GenBank acession AF263523
Entrez gene record 59341
Pubmed identfication 11025659 11081638 16382100 20037587
RefSeq identity NM_021625
Classification Ankyrin repeat domain containing Transient receptor potential cation channels
Havana BLAST/BLAT OTTHUMG00000169277
Locus Specific Databases LRG_372

Similar products

Subscribe to our Newsletter