Name : TRPM8 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6285401503
| Long name | TRPM8 Primary Polyclonal Antibody |
| Also known as | TRPM8 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | TRPM8 |
| Specificity | This is a highly specific antibody against TRPM8 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRPM8 |
| Gene ID number | 79054 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Activated by icilin, Activated upon depolarization, Involved in menthol sensation, Permeable for monovalent cations sodium, Temperature sensing is tightly linked to voltage-dependent gating, Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing, The chemical agonists menthol functions as a gating modifier, and cesium and divalent cation calcium, by being activated by cold temperature below 25 degrees Celsius, changes in temperature resulting in graded shifts of its voltage-dependent activation curves, cold and modulation of intracellular pH, eucalyptol, menthol, potassium, shifting activation curves towards physiological membrane potentials, Receptor-activated non-selective cation channel involved in detection of sensations such as coolness |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | LTrpC6 antibody Short form of the TRPM8 cationic channel, Long transient receptor potential channel 6, MGC2849, TRPM8_HUMAN, TRPP8, Transient receptor potential cation channel subfamily M member 8, Transient receptor potential p8, Trp p8, Trp-p8, Trpm8, transient receptor potential-p8, LTrpC-6 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | TRPM8 |
| Short name | TRPM8 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | TRPM8 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17961 |
| Gene | TRPM8 |
| Long gene name | transient receptor potential cation channel subfamily M member 8 |
| Synonyms gene name | member 8 , subfamily M, transient receptor potential cation channel |
| Locus | 2q37, 1 |
| Discovery year | 2002-01-11 |
| GenBank acession | AC005538 |
| Entrez gene record | 79054 |
| Pubmed identfication | 16382100 |
| RefSeq identity | NM_024080 |
| Classification | Transient receptor potential cation channels |
| Havana BLAST/BLAT | OTTHUMG00000059129 |