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UVRAG Antibody

UVRAG Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameUVRAG Primary Polyclonal Antibody
Also known asUVRAG PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenUVRAG
SpecificityThis is a highly specific antibody against UVRAG
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UVRAG/DHTX
Gene ID number7405
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Autophagy is the degradation of cellular proteins in the lysosomes, Mutations in the gene encoding UVRAG have been associated with colon cancer, UVRAG contains one C2 domain, UVRAG has been found to complement the ultraviolet sensitivity of xeroderma pigmentosum group C cells, UVRAG has been shown to activate the BECN1/PI 3-kinase complex, UVRAG is found at highest levels in kidney, Ubiquitously expressed, also known as p63 or DHTX, and when this pathway is suppressed, cell growth is deregulated, is a 699 amino acid cytoplasmic protein, liver and brain, lung, suggesting that UVRAG is also involved in suppressing the proliferation and tumorigenicity of human colon cancer cells, which is thought to be involved in calcium-dependent phospholipid binding, which promotes autophagy, UVRAG
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Disrupted in heterotaxy, UV radiation resistance associated, UV radiation resistance associated gene, UV radiation resistance associated gene protein, UV radiation resistance-associated gene protein, UVRAG, UVRAG_HUMAN, p63, DHTX
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetUVRAG
Short nameUVRAG Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameUVRAG (Antibody to)
Alternative techniqueantibodies
Identity 12640
Gene UVRAG
Long gene name UV radiation resistance associated
Synonyms gene name UV radiation resistance associated gene
Synonyms VPS38
Synonyms name beclin 1 binding protein
Locus 11q13, 5
Discovery year 1997-01-10
GenBank acession X99050 AB012958
Entrez gene record 7405
Pubmed identfication 9169138 16799551 18843052
RefSeq identity NM_003369
Classification C2 domain containing
Havana BLAST/BLAT OTTHUMG00000165319

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