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WAVE 1 Antibody

WAVE 1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameWAVE 1 Primary Polyclonal Antibody
Also known asWAVE 1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenWAVE 1
SpecificityThis is a highly specific antibody against WAVE 1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human WAVE 1
Gene ID number8936
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating Actin reorganization downstream of the Rho family of small GTPases, The protein homologs WAVE1 and WAVE2 regulate membrane ruffling by inducing the formation of Actin filament clusters in response to GTP binding and by activating Rac, They mediate Actin polymerization by cooperating with the Arp2/3 complex, WAVE1, WAVE3 forms a multiprotein complex that links receptor kinases with Actin and plays a role in the transduction of signals involving changes in cell shape, function or motility, is expressed primarily in the brain, thereby promoting the formation of Actin filaments, which accumulate at focal adhesions and are also involved in the regulation of the Actin cytoskeleton, which is also designated SCAR (suppressor of cAR), while WAVE2 is widely expressed, with the expression highest in peripheral blood leukocytes, WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in Actin polymerization and cytoskeletal organization
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Protein WAVE1, SCAR1, Similar to a plant extensin like protein, Verprolin homology domain containing protein 1, Verprolin homology domain-containing protein 1, WAS protein family, WASF1_HUMAN, WASL, WASP family 1, WASP family protein member 1, WAVE, WAVE1, Wasf1, Wiskott Aldrich syndrome protein family member 1, Wiskott-Aldrich syndrome protein family member 1, member 1, Protein WAVE-1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetWAVE 1
Short nameWAVE 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameWAVE 1 (Antibody to)
Alternative techniqueantibodies
Identity 12732
Gene WASF1
Long gene name WAS protein family member 1
Synonyms gene name WAS protein family, member 1
Synonyms WAVE1 SCAR1 KIAA0269 WAVE
Locus 6q21
Discovery year 1999-09-21
GenBank acession D87459
Entrez gene record 8936
Pubmed identfication 9843499 9889097
RefSeq identity NM_003931
Classification A-kinase anchoring proteins Wiskott-Aldrich Syndrome protein family
Havana BLAST/BLAT OTTHUMG00000015357

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