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Yellow fever virus envelope glycoprotein E Antibody

Yellow fever virus envelope glycoprotein E Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameYellow fever virus envelope glycoprotein E Antibody
Also known asYellow fever virus envelope glycoprotein E Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenYellow fever virus envelope glycoprotein E
SpecificityThis is a highly specific antibody against Yellow fever virus envelope glycoprotein E
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range650-700/3411
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from Yellow fever virus envelope glycoprotein E (IIVGRGDSRLTY)
Gene ID number1502173
Swiss ProtP03314
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivityVirus
Cross reactive species detailsYellow fever virus
Background of the target antigen After cleavage by host furin, After cleavage of prM, Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis, Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes, NS2A-NS2B, NS2B-NS3, NS3 RNA helicase binds RNA and unwinds dsRNA in the 3' to 5' direction (By similarity), NS3 serine protease, NS3-NS4A, NS4A-2K and NS4B-NS5, NTPase and RNA helicase, Non-structural protein 1 is involved in virus replication and regulation of the innate immune response, Non-structural protein 2A may be involved viral RNA replication and capsid assembly, Non-structural protein 2B is a required cofactor for the serine protease function of NS3, Non-structural protein 4A induces host endoplasmic reticulum membrane rearrangements leading to the formation of virus-induced membranous vesicles hosting the dsRNA and polymerase, Serine protease NS3 displays three enzymatic activities: serine protease, Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E, The capsid encapsulates the genomic RNA (By similarity), envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity), functioning as a replication complex, in association with NS2B, performs its autocleavage and cleaves the polyprotein at dibasic sites in the cytoplasm: C-prM, prM acts as a chaperone for envelope protein E during intracellular virion assembly by masking and inactivating envelope protein E fusion peptide, prM is matured in the last step of virion assembly, presumably to avoid catastrophic activation of the viral fusion peptide induced by the acidic pH of the trans-Golgi network, the pr peptide is released in the extracellular medium and small envelope protein M and envelope protein E homodimers are dissociated (By similarity), Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym namesGenome polyprotein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetfever virus envelope glycoprotein E
Short namefever virus envelope glycoprotein E Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameYellow fever virus envelope glycoprotein E (Antibody to)
Alternative techniqueantibodies

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