Name : ZNRF2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1732371864
| Long name | ZNRF2 Primary Polyclonal Antibody |
| Also known as | ZNRF2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ZNRF2 |
| Specificity | This is a highly specific antibody against ZNRF2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZNRF2 |
| Gene ID number | 223082 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Expressed at high levels in brain tissue, The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), Upon DNA damage, ZNRF2 (zinc and ring finger 2), ZNRF2 is subject to phosphorylation, ZNRF2 is thought to function as an E3 ubiquitin-protein ligase that may be involved in the establishment and maintenance of neuronal transmission and plasticity, also known as RNF202, as well as the endosome and the cell junction, is a 242 amino acid peripheral membrane protein that contains one RING-type zinc finger and localizes to the lysosome, probably by ATR or ATM, the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s), Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Protein Ells2, RING finger protein 202, ZNRF2_HUMAN, Zinc/RING finger protein 2, Znrf2, E3 ubiquitin-protein ligase ZNRF2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ZNRF2 |
| Short name | ZNRF2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | ZNRF2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 22316 |
| Gene | ZNRF2 |
| Long gene name | zinc and ring finger 2 |
| Synonyms gene name | E3 ubiquitin protein ligase , zinc and ring finger 2 |
| Synonyms | RNF202 |
| Locus | 7p14, 3 |
| Discovery year | 2004-07-29 |
| GenBank acession | AF513707 |
| Entrez gene record | 223082 |
| Pubmed identfication | 22797923 |
| RefSeq identity | NM_147128 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000097759 |