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AR Antibody

AR Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAR
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the AR antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis AR antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P10275
PurityAntigen affinity
Description DNA-binding domain, Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease), Mutations in this gene are also associated with complete androgen insensitivity (CAIS), The protein functions as a steroid-hormone activated transcription factor, This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein, Two alternatively spliced variants encoding distinct isoforms have been described, Upon binding the hormone ligand, [provided by RefSeq], and androgen-binding domain, and then stimulates transcription of androgen responsive genes, dimerizes, the receptor dissociates from accessory proteins, translocates into the nucleus, The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain
ImmunogenA portion of amino acids 282-309 from the human protein was used as the immunogen for this AR antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the AR antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetAR
Short nameAR Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAR (Antibody to)
Alternative techniqueantibodies
Identity 10543
Gene SBMA
Long gene name aldo-keto reductase family 1 member B
Synonyms gene ALDR1
Synonyms gene name aldo-keto reductase family 1, member B1 (aldose reductase)
Synonyms AR AR
Synonyms name aldose reductase
Locus 7q33
Discovery year 1991-08-07
GenBank acession J04795
Entrez gene record 231
Pubmed identfication 1901827
RefSeq identity NM_001628
Classification Aldo-keto reductases
Havana BLAST/BLAT OTTHUMG00000155322

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