| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | ARC |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB |
| Recommended dilutions | Western blot: 1:1000 |
| Notes | Titration of the ARC antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This ARC antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q7LC44 |
| Purity | Antigen affinity |
| Description | Regulates endocytosis of AMPA receptors in response to synaptic activity, Required for homeostatic synaptic scaling of AMPA receptors (By similarity), ARC (Activity-Regulated Cytoskeleton-associated protein) is required for consolidation of synaptic plasticity as well as formation of long-term memory |
| Immunogen | A portion of amino acids 37-66 from the human protein was used as the immunogen for this ARC antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ARC antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | ARC |
| Short name | ARC Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | activity-regulated cytoskeleton-associated protein (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | ARC and IDBG-37634 and ENSG00000198576 and 23237, ARC and IDBG-648018 and ENSBTAG00000021639 and 519403, Arc and IDBG-149967 and ENSMUSG00000022602 and 11838, Arg3, Cell surfaces, protein binding, this GO :0001669 and acrosomal vesicle and cellular component this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006897 and endocytosis and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007492 and endoderm development and biological process this GO :0007612 and learning and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0014069 and postsynaptic density and cellular component this GO :0015629 and actin cytoskeleton and cellular component this GO :0016477 and cell migration and biological process this GO :0022604 and regulation of cell morphogenesis and biological process this GO :0030054 and cell junction and cellular component this GO :0043197 and dendritic spine and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0048168 and regulation of neuronal synaptic plasticity and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, 1, activity-regulated cytoskeleton-associated protein |
| Identity | 648 |
| Gene | ARC |
| Long gene name | activity regulated cytoskeleton associated protein |
| Synonyms | KIAA0278 Arg3, 1 |
| Locus | 8q24, 3 |
| Discovery year | 2000-05-23 |
| GenBank acession | AF193421 |
| Entrez gene record | 23237 |
| Pubmed identfication | 10970730 17466953 |
| Havana BLAST/BLAT | OTTHUMG00000134310 |