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ARHGAP24 Antibody

ARHGAP24 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameARHGAP24 Primary Polyclonal Antibody
Also known asARHGAP24 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenARHGAP24
SpecificityThis is a highly specific antibody against ARHGAP24
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range630-680/748
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARHGAP24
Gene ID number83478
Swiss ProtQ8N264
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Able to suppress RAC1 and CDC42 activity in vitro, Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state, Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity, Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis, Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, and filopodia, cell morphology and cytoskeletal organization, lamellipodia, Rho GTPase-activating protein involved in cell polarity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ARHGAP24, FILGAP, FilGAP, Filamin-A-associated RhoGAP, RAC1- and CDC42-specific GTPase-activating protein of 72 kDa, RC-GAP72, Rho-type GTPase-activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY-SAR-88, p73RhoGAP, Rho GTPase-activating protein 24
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetARHGAP24
Short nameARHGAP24 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameARHGAP24 (Antibody to)
Alternative techniqueantibodies
Identity 25361
Gene ARHGAP24
Long gene name Rho GTPase activating protein 24
Synonyms DKFZP564B1162 FLJ33877 FilGAP
Locus 4q21, 23-q21, 3
Discovery year 2004-04-06
GenBank acession AK091196
Entrez gene record 83478
Pubmed identfication 11230166 15254788
RefSeq identity NM_031305
Classification Pleckstrin homology domain containing Rho GTPase activating proteins
Havana BLAST/BLAT OTTHUMG00000130427

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