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ATXN1 (Ser775) Antibody

ATXN1 (Ser775) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameATXN1 (Ser775) Primary Polyclonal Antibody
Also known asATXN1 (Ser775) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenATXN1 Ser775
SpecificityThis is a highly specific antibody against ATXN1 Ser775
Modification(s)Phosphorylation
Modification site(s)Ser775
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human Ataxin-1 around the phosphorylation site of Ser775
Gene ID number6310
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 2, 3, 4 and 6, ADCA has been divided into three groups: ADCA types I-III, ADCA is caused by the expansion of the CAG repeats, ADCAI is genetically heterogeneous, ADCAII, At least two transcript variants encoding the same protein have been found for this gene, Clinically, Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions, The expanded repeats are variable in size and unstable, The function of the ataxins is not known, This locus has been mapped to chromosome 6, [provided by RefSeq], and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), and is associated with spinocerebellar ataxia type 1 (SCA1), and it has been determined that the diseased allele contains41-81 CAG repeats, are most likely homogeneous disorders, being assigned to five different chromosomes, brain stem and spinal cord, compared to 6-39 in the normal allele, designated spinocerebellar ataxia (SCA) 1, producing an elongated polyglutamine tract in the corresponding protein, usually increasing in size when transmitted to successive generations, which always presents with retinal degeneration (SCA7), with five genetic loci, The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ATX1, ATX1_HUMAN, Ataxin-1, D6S504E, SCA1, Spinocerebellar ataxia type 1, ATXN1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetATXN1 (Ser775)
Short nameATXN1 (Ser775) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameATXN1 (Ser775) (Antibody to)
Alternative techniqueantibodies
Identity 10548
Gene ATXN1
Long gene name ataxin 1
Synonyms gene SCA1
Synonyms gene name ataxin 1) , autosomal dominant, spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1
Synonyms D6S504E ATX1
Locus 6p22, 3
Discovery year 1986-01-01
GenBank acession X79204
Entrez gene record 6310
Pubmed identfication 1582256
RefSeq identity NM_000332
Classification Ataxins
Havana BLAST/BLAT OTTHUMG00000014303
Locus Specific Databases LRG_863

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