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BRCC45 Antibody

BRCC45 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBRCC45 Primary Polyclonal Antibody
Also known asBRCC45 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBRCC45
SpecificityThis is a highly specific antibody against BRCC45
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BRCC45
Gene ID number9577
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen At least three isoforms of BRCC45 are known to exist, BRCC45 has also been suggested to function as a death receptor associated anti apoptotic protein by inhibiting the BID induced activation of the mitochondrial apoptotic pathway, Higher levels of BRCC45 were detected in the majority of hepatocellular carcinomas, Later experiments indicated BRCC45 forms a complex with the breast and ovarian predisposition proteins BRCA1 and BRCA2 as well as RAD51 and BRCC36, This complex has a ubiquitin E3 ligase activity and is thought to enhance cellular survival following DNA damage, suggesting that BRCC45 may promote tumorigenesis when overexpressed, BRCC45 was initially suggested to be a housekeeping protein that is highly expressed in brain and reproductive organs
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BRCA1/BRCA2 containing complex subunit 4, BRCA1/BRCA2 containing complex subunit 45, BRCC4, BRCC45, BRE_HUMAN, Brain and reproductive organ expressed TNFRSF1A modulator
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBRCC45
Short nameBRCC45 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBRCC45 (Antibody to)
Alternative techniqueantibodies
Identity 1106
Gene BRE
Long gene name brain and reproductive organ-expressed (TNFRSF1A modulator)
Synonyms BRCC45 BRCC4
Synonyms name BRCA1/BRCA2-containing complex, subunit 4
Locus 2p23, 2
Discovery year 1999-04-23
GenBank acession AF015767
Entrez gene record 9577
Pubmed identfication 9737713 7826398
Classification BRISC complex BRCA1 A complex
Havana BLAST/BLAT OTTHUMG00000097831

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