Name : CYP21 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5113207524
| Long name | CYP21 Primary Polyclonal Antibody |
| Also known as | CYP21 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CYP21 |
| Specificity | This is a highly specific antibody against CYP21 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 130-180/494 |
| Subcellular location | Cell membrane, Membrane bound |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CYP21 |
| Gene ID number | 1589 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | A related pseudogene is located near this gene, Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone, Mutations in this gene cause congenital adrenal hyperplasia, The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position, Two transcript variants encoding different isoforms have been found for this gene, [provided by RefSeq], gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency, steroids and other lipids, This gene encodes a member of the cytochrome P450 superfamily of enzymes |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 21-OH, 21OHA, 21OHB, CA21H, CAH1, CHOLESTEROL 21-HYDROXYLASE, CP21A_HUMAN, CPS1, CYP21, CYP21A2, CYP21A2, CYP21B, CYP21OH-A, Cyp21-ps1, Cyp21a1, Cyp21a2-ps, MGC150536, MGC150537, MGC156449, Oh21-1, Oh21-2, P450C21, P450c21B, cytochrome P450, family 21, polypeptide 2, subfamily A, Cytochrome P450 21 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CYP21 |
| Short name | CYP21 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CYP21 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2600 |
| Gene | CYP21A2 |
| Long gene name | cytochrome P450 family 21 subfamily A member 2 |
| Synonyms gene | CYP21 CYP21B |
| Synonyms gene name | congenital adrenal hyperplasia), cytochrome P450, family 21, polypeptide 2 , polypeptide 2 cytochrome P450, subfamily A, subfamily XXIA (steroid 21-hydroxylase |
| Synonyms | P450c21B CA21H CPS1 CAH1 |
| Synonyms name | Steroid 21-monooxygenase |
| Locus | 6p21, 33 |
| Discovery year | 1986-01-01 |
| GenBank acession | X58906 |
| Entrez gene record | 1589 |
| RefSeq identity | NM_000500 |
| Classification | Cytochrome P450 family 21 |
| Havana BLAST/BLAT | OTTHUMG00000031069 |
| Locus Specific Databases | Human Cytochrome P450 (CYP) Allele Nomenclature Committee LRG_829 |