Name : DIS3L Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN9918562289
| Long name | DIS3L Primary Polyclonal Antibody |
| Also known as | DIS3L PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | DIS3L |
| Specificity | This is a highly specific antibody against DIS3L |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DIS3L |
| Gene ID number | 115752 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Abnormal expression levels of DIS3 may be associated with colon cancer, DIS3, DIS3 functions as a component of the exosome exoribonuclease complex and is required for processing of 7S pre-RNA into a mature nuclear complex and, Multiple isoforms of DIS3 exist due to alternative splicing events, The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements (AREs) in their untranslated 3â, Widely expressed with highest expression in testis, also known as RRP44, exoribonucleases, for proper mitotic progression, is a 958 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one PINc domain, regions, some of which are 3â, suggesting a role for DIS3 in tumorigenesis, to 5â, ultimately, &euro, &euro, &euro, &trade, &trade, &trade, The exosome is a multi-protein complex composed of several highly conserved subunits |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DI3L1_HUMAN, DIS3 mitotic control homolog S, FLJ38088, KIAA1955, MGC4562, cerevisiae like, DIS3 like exonuclease 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DIS3L |
| Short name | DIS3L Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | DIS3L (Antibody to) |
| Alternative technique | antibodies |
| Identity | 28698 |
| Gene | DIS3L |
| Long gene name | DIS3 like exosome 3', exoribonuclease , -5' |
| Synonyms gene name | DIS3 mitotic control homolog (S, cerevisiae)-like |
| Synonyms | MGC4562 FLJ38088 KIAA1955 DIS3L1 |
| Locus | 15q22, 31 |
| Discovery year | 2007-01-12 |
| Entrez gene record | 115752 |
| Pubmed identfication | 20531386 |
| RefSeq identity | NM_133375 |
| Classification | Exosome complex |
| Havana BLAST/BLAT | OTTHUMG00000133181 |