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Dnmt3L Antibody

Dnmt3L Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDnmt3L Primary Polyclonal Antibody
Also known asDnmt3L PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDnmt3L
SpecificityThis is a highly specific antibody against Dnmt3L
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dnmt3L
Gene ID number29947
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Additionally, DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, Dnmt3L (DNA (cytosine-5)-methyltransferase 3-like) is a 387 amino acid protein that contains one ADD-type zinc finger and is a member of the Dnmt family, Dnmt3L does not exhibit DNA methyltransferase activity, Dnmt3L interacts with histone deacetylase 1 (HDAC1) and, Localized to the nucleus and expressed at lows levels in thymus, Multiple isoforms of Dnmt3L exist due to alternative splicing events, but is able to stimulate de novo methylation by Dnmt3 and is thought to play a key role in the establishment of genomic imprints, mediates transcriptional repression, testis and ovary, thereby repressing expression of the target gene, through this interaction, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines, Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DNA Cytosine 5 Methyltransferase 3 Like Protein, DNA Methyltransferase 3 Like Protein, DNA cytosine 5 methyltransferase 3 like, DNA cytosine-5-methyltransferase 3-like, DNM3L_HUMAN, Dnmt 3L, Dnmt3l, Human cytosine 5 methyltransferase 3 like protein, MGC1090, Cytosine 5 methyltransferase 3 like protein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDnmt3L
Short nameDnmt3L Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDnmt3L (Antibody to)
Alternative techniqueantibodies
Identity 2980
Gene DNMT3L
Long gene name DNA methyltransferase 3 like
Synonyms gene name DNA (cytosine-5-)-methyltransferase 3-like
Synonyms MGC1090
Synonyms name cytosine-5-methyltransferase 3-like protein
Locus 21q22, 3
Discovery year 2000-05-23
GenBank acession AF194032
Entrez gene record 29947
Pubmed identfication 10857753
RefSeq identity NM_013369
Havana BLAST/BLAT OTTHUMG00000086914

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