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EML4 Antibody

EML4 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameEML4 Primary Polyclonal Antibody
Also known asEML4 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEML4
SpecificityThis is a highly specific antibody against EML4
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EML4/C2orf180
Gene ID number27436
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen C2orf2 or ROPP120, Due to a chromosomal inversion with chromosome 2p, ELP120, EML4 (Echinoderm microtubule-associated protein-like 4), EML4 is thought to modify the assembly dynamics of microtubules, EML4 may exist as a fusion protein with ALK (anaplastic lymphoma receptor tyrosine kinase), Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules, Expressed at high levels during mitosis, also known as EMAPL4, cell motility, is a 981 amino acid cytoplasmic protein that contains nine WD repeats, producing an EML4-ALK fusion complex that plays a role in the pathogenesis of lung cancer, specifically altering microtubules to become longer and more flexible, spindle formation and chromosome movements, Microtubules are components of the Actin cytoskeleton that play crucial roles in cell morphogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C2orf2, ELP 120, ELP120, EMAL4_HUMAN, EMAP 4, EMAP-4, EMAP4, EML 4, EML-4, Echinoderm microtubule associated protein like 4, Echinoderm microtubule-associated protein-like 4, ROPP120, Restrictedly overexpressed proliferation associated protein, Restrictedly overexpressed proliferation-associated protein, Ropp 120, eml4, EML4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetEML4
Short nameEML4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEML4 (Antibody to)
Alternative techniqueantibodies
Identity 1316
Gene EML4
Long gene name echinoderm microtubule associated protein like 4
Synonyms gene C2orf2
Synonyms ROPP120 ELP120
Locus 2p21
Discovery year 2000-01-31
GenBank acession AF177377
Entrez gene record 27436
RefSeq identity NM_019063
Classification WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000128603

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