Name : EMP1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8164445783
| Long name | EMP1 Primary Polyclonal Antibody |
| Also known as | EMP1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | EMP1 |
| Specificity | This is a highly specific antibody against EMP1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 105-135/160 |
| Subcellular location | Cell membrane |
| Source | KLH conjugated synthetic peptide derived from mouse Emp1 |
| Gene ID number | 13730 |
| Swiss Prot | P47801 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Rat, Mouse |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing, EMP-1 is very similar in structure to its close relative, EMP-1 may also be an important regulator in cell communication, EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer, It is a member of a small family of epithelial membrane proteins, It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border, Peripheral Myelin Protein 22 (PMP22), S phase is arrested and G1 phase is prolonged in esophogeal cancer cells, When EMP-1 is overexpressed, and adhesion, cell proliferation is inhibited, signaling, Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | EMP-1, Emp1, Epithelial membrane protein 1, I-8-9, Tumor-associated membrane protein, TMP |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | EMP1 |
| Short name | EMP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | EMP1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3333 |
| Gene | EMP1 |
| Long gene name | epithelial membrane protein 1 |
| Synonyms | TMP CL-20 |
| Locus | 12p13, 1 |
| Discovery year | 1997-12-05 |
| GenBank acession | U43916 |
| Entrez gene record | 2012 |
| Pubmed identfication | 8996089 9126480 |
| RefSeq identity | NM_001423 |
| Havana BLAST/BLAT | OTTHUMG00000168775 |