Name : FBXW12 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN9181909297
| Long name | FBXW12 Primary Polyclonal Antibody |
| Also known as | FBXW12 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | FBXW12 |
| Specificity | This is a highly specific antibody against FBXW12 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FBXW12/FBXO35 |
| Gene ID number | 285231 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, FBXO35 (F-box only protein 35), FBXO35 can directly interact with Skp1 p19 and CUL-1, FBXO35 is ubiquitously expressed at low levels in most human tissues, I&, They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, They function by targeting proteins, Via its F-box domain, also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), and â, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, including the cell cycle, is a 464 amino acid protein that contains one C-terminal F-box domain, signaling cascades and developmental processes, such as cyclins, the immune response, #730, &circ, «, -catenin, B-&, Belonging to the F-box family of proteins, aring |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | F box and WD 40 domain protein 12, F box and WD repeat domain containing 12, F box and WD40 repeat containing protein, F box only protein 35, F box/WD repeat containing protein 12, F-box and WD-40 domain-containing protein 12, F-box only protein 35, F-box/WD repeat-containing protein 12, FBW12_HUMAN, FBX12, FBXO12, FBXO35, FBXW 12, FBXW12, Fbw12, F box and WD 40 domain containing protein 12 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FBXW12 |
| Short name | FBXW12 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | FBXW12 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 20729 |
| Gene | FBXW12 |
| Long gene name | F-box and WD repeat domain containing 12 |
| Synonyms gene | FBXO35 |
| Synonyms gene name | F-box only protein 35 F-box and WD-40 domain protein 12 |
| Synonyms | Fbw12 |
| Locus | 3p21, 31 |
| Discovery year | 2003-04-04 |
| GenBank acession | AK097594 AY247969 |
| Entrez gene record | 285231 |
| Pubmed identfication | 15040455 |
| RefSeq identity | NM_207102 |
| Classification | F-box and WD repeat domain containing WD repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000133530 |