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Gliomedin Antibody

Gliomedin Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGliomedin Primary Polyclonal Antibody
Also known asGliomedin PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGliomedin
SpecificityThis is a highly specific antibody against Gliomedin
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Gliomedin/COLM
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Accumulation of Na+ channels at the nodes of Ranvier is a prerequisite for saltatory conduction, Gliomedin is a glial ligand for Neurofascin and NrCAM, Gliomedin is a single-pass type II membrane protein localized to the nodes of Ranvier and is specifically expressed in spinal cord, Gliomedin is expressed by myelinating Schwann cells and accumulates at the edges of each myelin segment during development, Gliomedin is thought to play a role in the formation of the nodes of Ranvier along myelinated axons, In peripheral nerves, It is more abundant in peripheral than central nervous system, brain, clustering of these channels along the axolemma is regulated by myelinating Schwann cells through an unknown mechanism, placenta and sciatic nerve, two axonal immunoglobulin cell adhesion molecules that are associated with Na+ channels at the nodes of Ranvier, where it aligns with the forming nodes, Gliomedin is a 551 amino acid protein encoded by the human gene GLDN
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CLOM, COLM, CRG L2, Cancer related gene-Liver 2, Colm gene name, Colmedin, FLJ23917, GLDN_HUMAN, Gldn gene name, UNC 112, collomin, CANCER RELATED GENE LIVER 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGliomedin
Short nameGliomedin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGliomedin (Antibody to)
Alternative techniqueantibodies
Identity 29514
Gene GLDN
Long gene name gliomedin
Synonyms gene COLM
Synonyms gene name collomin
Synonyms CRG-L2 CLOM colmedin UNC-112
Locus 15q21, 2
Discovery year 2004-05-18
GenBank acession AY358144
Entrez gene record 342035
Pubmed identfication 16039564 12642876
RefSeq identity NM_181789
Havana BLAST/BLAT OTTHUMG00000131746

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