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HAS3 Antibody

HAS3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHAS3 Primary Polyclonal Antibody
Also known asHAS3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHAS3
SpecificityThis is a highly specific antibody against HAS3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HAS3
Gene ID number3038
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Both HAS1 and HAS2 synthesize high molecular-weight HA, HAS2 and HAS3 are HA (hyaluronan or hyaluronic acid) synthase proteins, HAS3 gene expression plays a crucial role in the regulation of hyaluronan synthesis in the epidermis, HAS3 produces both secreted and cell-associated forms of hyaluronan and is the most active of the three isoforms of this enzyme in adults, IFN-g markedly upregulates HAS3 mRNA, Specifically, The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli, The extracellular matrix in most vertebrates express HA, The human HAS3 gene maps to chromosome 16q22, The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix, suggesting distinct functional roles of the three proteins, whereas HAS3 produces lower molecular weight HA, whereas TGF Beta downregulates HAS3 transcript levels, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by b-1, 1, 3 and b-1, 4 glycosidic bonds, HAS1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names HAS 3, HAS-3, HAS3, HAS3_HUMAN, Hyaluronan synthase 3, Hyaluronate synthase 3, Hyaluronic acid synthase 3, HA synthase 3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHAS3
Short nameHAS3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHAS3 (Antibody to)
Alternative techniqueantibodies
Identity 4820
Gene HAS3
Long gene name hyaluronan synthase 3
Locus 16q22, 1
Discovery year 1996-10-18
GenBank acession BC021853
Entrez gene record 3038
Pubmed identfication 9169154 9083017
RefSeq identity NM_138612
Classification Glycosyltransferase family 2
Havana BLAST/BLAT OTTHUMG00000137562

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